2018-present independent career

Chilamari, M.; Immel, J. R.; Chen, P.-H.; Alghafli, B. M.; Bloom, S.


Zhang, L.; Floyd, B. M.; Chilamari, M.; Mapes, J.; Swaminathan, J.; Bloom, S.; Marcotte, E. M.; Anslyn, E. V.


Combining Flavin Photocatalysis with Parallel Synthesis: A General Platform to Optimize Peptides with Non-Proteinogenic Amino Acids

Chemical Science

Immel, J. R.; Chilamari, M.; Bloom, S.

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Site-selective tyrosine bioconjugation via photoredox catalysis for native-to-bioorthogonal protein transformation

Nature Chemistry

Li, B. X.; Kim, D. K.; Bloom, S.; Huang, R. Y.-C.; Qiao, J. X.; Ewing, W. R.; Oblinsky, D. G.; Scholes, G. D.; MacMillan, D. W. C.

Solid-phase XRN1 Reactions for RNA Cleavage: Application in Single-Molecule Sequencing

Nucleic Acids Research

Athapattu, U. S.; Amarasekara, C. A.; Immel, J. R.; Bloom, S.; Barany, F.; Nagel, A. C.; Soper, S. A. 

General Access to C-Centered Radicals: Combining a Bioinspired Photocatalyst

with Boronic Acids in Aqueous Media

ACS Catalysis

Chilamari, M.; Immel, J.; Bloom, S.

2016-2018 Postdoctoral work

Decarboxylative Alkylation for Site-Selective Bioconjugation of Native Proteins via Oxidation Potentials.

Nat. Chem.

Bloom, S.; Liu, C.; Kolmel, D. K.; Qiao, J. X.; Zhang, Y.; Poss, M. A.; Ewing, W. R.; MacMillan, D. W. C.

2011-2015 Graduate Work

Site-Selective Approach to B-Fluorination: Photocatalyzed Ring Opening of Cyclopropanols.

Chem. Eur. J.

Bloom, S.; Blume, D.; Pitts, C. R.; Lectka, T.

Photocatalyzed Benzylic Fluorination: Shedding “Light” on the Involvement of Electron Transfer.

Org. Lett.

Bloom, S.; McCann, M.; Lectka, T.

A Chealting Nucleophile Plays a Starring Role: 1,8-Naphthyridine-Catalyzed Polycomponent a,a-Difluorination of Acid Chlorides.

J. Org. Chem.

Griswold, A.; Bloom, S.; Lectka, T.

A Cooperative Allylic Flourination: Combination of Nucleophilic and Electrophilic. Fluorine Sources.

Tetrahedron Lett.

Bloom, S.; Knippel, J. L.; Holl, M. G.; Barber, R.; Lectka, T.

Direct, Catalytic Monofluorination of sp3 C-H Bonds: A Radical-Based Mechanism with Ionic Selectivity.

J. Am. Chem. Soc.

Pitts, C. R.; Bloom, S.; Woltornist, R.; Auvenshine, D.; Ryzhkov, L. R.; Siegler, M. A.; Lectka, T.

A Photocatalyzed Aliphatic Flourination.

Chem. Sci.

Bloom, S.; Knippel, J. L.; Lectka, T.

Metal-Catalyzed Benzylic Flourination as a Synthetic Equivalent to 1,4-Conjugate Addition of Fluoride

J. Org. Chem.

Bloom, S.; Sharber, S. A.; Holl, M. G.; Knippel, J. L.; Lectka, T.

Origin of the Diffuse Vibrational Signature of a Cyclic Intramolecular Proton Bond: Anharmonic Analysis of Protonated 1,8-Disubstituted Naphthalene Ions.

J. Phys. Chem.

DeBlase, A. F.; Bloom, S.; Dudding, T.; Lectka, T.; Johnson, M. A.

Iron(II)-Catalyzed Benzylic Fluorination.

Org. Lett.

Bloom, S.; Pitts, C. R.; Woltornist, R.; Griswold, A.; Holl, M. G.; Lectka, T.

A Polycomponent Metal-Catalyzed Aliphatic, Allylic, and Benzylic Flourination.

Angew. Chem.

Bloom, S.; Pitts, C. R.; Miller, D.; Haselton, N.; Holl, M. G.; Urheim, E.; Lectka, T.

Interaction of a C-F Bond with the pi-System of a C=C Bond or ‘Head On’ with a Proximate C-H Bond.

J. Org. Chem.

Scerba, M. T.; Bloom, S.; Haselton, N.; Siegler, M.; Jaffe, J.; Lectka, T.

Characterization of Highly Unusual NH+-O Hydrogen Bonding to Ester Ether Oxygen Atoms through Spectroscopic and Computational Studies.

J. Phys. Chem. A

Scerba, M. T.; DeBlase, A. F.; Bloom, S.; Dudding, T.; Johnson, M. A.; Lectka, T.

Tricomponent Catalytic a,a-Difluorination of Acid Chlorides.

Org. Lett.

Bloom, S.; Scerba, M. T.; Erb, J.; Lectka, T.


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Photoredox catalysis, peptide therapeutics, biologics, targets, drug discovery, Pharma, Pharma, Bloom, Steve Bloom, The Bloom Group, KU, Science, Peptides, research, unnatural amino acids, peptide libraries, biocompatible photocatalysts, tethering biomolecules, chemotherapeutics, photochemical strategies, fusion proteins, antibody conjugates, bi-specific peptides, light activated molecules, electron oxidation, synthetic radical intermediates, therapeutic scaffolds, medicinally relevant compounds, bio-derived therapeutics, small cell lung cancer, viral capsid, improved therapeutics,