Photoredox catalysis has emerged as an attractive tool for medicinal chemistry, streamlining both targeted drug synthesis and late-stage molecular editing. Research in the Bloom group seeks to harness this multifarious platform to address key challenges at the interface of synthetic chemistry and biotechnology.
Specifically, our group is interested in the use of photoredox catalysis for the synthesis of peptide and protein-based therapeutics. Among our current interests are the development of chemical methods for the controlled synthesis of non-classical peptides, peptibodies, fusion proteins, bispecific antibody constructs, and peptide/protein-based drug conjugates for use in targeted therapy.
2015-2018
Department of Chemistry, Princeton University, Princeton, NJ (Advisor: David W. C. MacMillan).
2012-2015
Organic Chemistry, Department of Chemistry, Johns Hopkins University, Baltimore, MD (Advisor: Thomas Lectka).
2010
B.A., Chemistry and Biochemistry
McDaniel College, Westminster, MD
2016-Present
National Institute of Health Ruth L. Kirschstein Fellowship
2015-2016
Bristol Myers Squibb Postdoctoral Fellowship (BMS-CMS)
2013
Owens Fellowship
2012
Gary H. Posner Fellowship
2010
Graduated with honors in chemistry and biochemistry from McDaniel College
2018
NAT. CHEM.
Bloom, S.; Liu, C.; Kolmel, D. K.; Qiao, J. X.; Zhang, Y.; Poss, M. A.; Ewing, W. R.; MacMillan, D. W. C.
2018, 10, 205-211.
2015
CHEM. EUR. J.
Bloom, S.; Blume, D.; Pitts, C. R.; Lectka, T.
2015, 21, 8060-8063.
2014
ORG. LETT.
Bloom, S.; McCann, M.; Lectka, T.
2014, 16, 6338-6341.
2014
J. ORG. CHEM.
Griswold, A.; Bloom, S.; Lectka, T.
2014, 79, 9830-9834.
2014
TETRAHEDRON LETT.
Bloom, S.; Knippel, J. L.; Holl, M. G.; Barber, R.; Lectka, T.
2014, 55, 4576-4580.
2014
J. AM. CHEM. SOC.
Pitts, C. R.; Bloom, S.; Woltornist, R.; Auvenshine, D.; Ryzhkov, L. R.; Siegler, M. A.; Lectka, T.
2014, 136, 9780-9791.
2014
CHEM. SCI.
Bloom, S.; Knippel, J. L.; Lectka, T.
2014, 5, 1175-1178.
2013
J. ORG. CHEM.
Bloom, S.; Sharber, S. A.; Holl, M. G.; Knippel, J. L.; Lectka, T.
2013, 78, 11082-11086.
2013
J. PHYS. CHEM.
DeBlase, A. F.; Bloom, S.; Dudding, T.; Lectka, T.; Johnson, M. A.
2013, 139, 024301.
2013
ORG. LETT.
Bloom, S.; Pitts, C. R.; Woltornist, R.; Griswold, A.; Holl, M. G.; Lectka, T.
2013, 15, 1722-1724.
2012
ANGEW. CHEM. INT. ED. ENGL.
Bloom, S.; Pitts, C. R.; Miller, D.; Haselton. N.; Holl, M. G.; Urheim, E.; Lectka, T. A
2012, 51, 10580-10583.
2012
J. ORG. CHEM.
Scerba, M. T.; Bloom, S.; Haselton, N.; Siegler, M.; Jaffe, J.; Lectka, T.
2012, 77, 1605-1609.
2012
J. PHYS. CHEM. A.
Scerba, M. T.; DeBlase, A. F.; Bloom, S.; Dudding, T.; Johnson, M. A.; Lectka, T.
2012, 116, 3556-3560
2011
ORG. LETT.
Bloom, S.; Scerba, M. T.; Erb, J.; Lectka, T.
Org. Lett. 2011, 13, 5068-5071.
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